Review Article
KEYWORDS- Dental Caries, Peptides, Remineralization
Year : 2022 | Volume : 10 | Issue : 1 | Page : 18 - 22
PEPTIDES IN REMINERALISATION - A REVIEW
Arungani NS 1, Kalaivani Venkadessan 2
1 Department of Oral Pathology and Microbiology, Indira Gandhi Institute of Dental Sciences, Pondicherry 2 Department of Public Health Dentistry, Saveetha Dental College and Hospitals, Vellapanchavadi, Poonamallee, Chennai- 600 077
Address for correspondence
Dr. Kalaivani V, Department of Public Health Dentistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai600077
E-mail address-kalai11venki@gmail.com
ABSTRACT
Caries develop when the remineralization and demineralization equilibriums are out of balance. When the demineralization level exceeds 30%, the enamel suffers irreversible damage. As a result, non-invasive techniques for early detection and management of these reversible incipient lesions are recommended. Fluorides are the most important and effective, and their local efficacy has been widely researched. Many new innovations have been introduced for remineralisation of the early lesions, such as ACP-CPP, Self-assembling peptides, etc., CPP–ACP is a milk product that aids in remineralization and dental caries prevention. Amorphous calcium phosphate is delivered by casein phosphopeptide, which also aids ACP binding to dental enamel. The natural amino acids Glutamine, Glutamic acid, Phenylalanine, Tryptophan, Serine, and Arginine make up the self-assembling peptide P11-4, which is intended to form brils at low pH and to be monomeric at higher pH. Furthermore, studies are to be conducted to learn about the mechanism of Self-assembling peptides.
KEYWORDS- Dental Caries, Peptides, Remineralization.
ACKNOWLEDGEMENT:
Nil
CONFLICT OF INTERESTS:
All the authors declare that there was no conflict of interest in the present study.
How to cite this article:Arungani NS, & Kalaivani Venkadessan. (2022). PEPTIDES IN REMINERALISATION - A REVIEW. International Journal of Community Dentistry, 10(1), 18–22. https://doi.org/10.56501/intjcommunitydent.v10i1.48
Received: 28-04-22; Accepted: 10-06-22; Web Published: 14-06-22.