Review Article
Year : 2018 | Volume : 1 | Issue : 1 | Page : 1-4
Diagnostic issue and caveats of immunoreactivity for Ki67 in hyalinizing trabecular neoplasm with review of literature: A study of one case
Veer Karuna, Priya Gupta, Mamta Gupta1 , Kriti Grover
Department of Pathology, L.L.R.M. Medical College, 1 Department of Pathology, Subharti Medical College, Meerut, Uttar Pradesh, India
Address for correspondence:
Dr. Veer Karuna, Department of Pathology, L.L.R.M. Medical College, Meerut, Uttar Pradesh, India.
E‐mail: dr.veera02@gmail.com
Abstract
Few benign and malignant thyroid lesions share many histological features including papillary and trabecular pattern, hyalinized stroma, calcification, nuclear grooving and nuclear inclusion. Well formalin fixed right lobe hemithyroidectomy specimen was received. After processing, H and E stain was done. Immunohistochemical studies (TTF, Thyroglobuline, MIB-1) and special stain (Congo red) were done to make a definite diagnosis. The present case describes a relatively rare thyroid tumour – Hyalinizing trabecular tumour with its varied morphological features creating diagnostic difficulties and role of IHC in formulating definitive diagnosis.
Keywords: Hyalinizing trabecular tumor, Ki67 (clone MIB-1 and SP6), papillary thyroid carcinoma
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Conflicts of interest
There are no conflicts of interest.
How to cite this article: Karuna V, Gupta P, Gupta M, Grover K. Diagnostic issue and caveats of immunoreactivity for Ki67 in hyalinizing trabecular neoplasm with review of literature: A study of one case. Int J Head Neck Pathol 2018;1:1-4.
