Review Article

Year : 2023 | Volume : 7 | Issue : 2 | Page : 37-41

Calcifying Odontogenic Cyst: An Enigma

Amisha Jain, BDS,MDS.1*| Himanshu Dhanodkar,BDS,MDS.2*|Anjali Shujalpurkar,BDS,MDS3*| Gauri Motiwale,BDS,MDS.2

Correspondence

Dr.AmishaJain,

Department of Oral and Maxillofacial Pathology, Modern Dental College&Research Center,Indore 453112, Madhya Pradesh, India

Email:jain.amisha01@gmail.com

Abstract

The calcifying odontogenic cyst (COC), discovered in 1962, is a rare developmental odontogenic cyst clinically present as slow-growing swelling mainly in the anterior portion of the jaws, generally present in the second and sixth decades of life. It accounts for 0.3%–0.8% of odontogenic cysts. COC showed variations in clinical and radiographic features that are not pathognomic, whereas histomorphology forms exist in 3 patterns: benign cystic, solid (neoplastic), and aggressive (malignant) forms. The radiograph shows well-defined radiolucency with irregular masses, while the histopathologic features include a cystic lining with characteristic “Ghost” cells and immunohistochemical reactions positive for various enamel proteins.

Keywords:

Calcifying odontogenic cyst, odontogenic cyst, review, COC, jaw, ghost cell

Funding information

Nil

Conflict of interest

The authors have no conflicts of interest

How to Cite this Article: Jain A, Dhanodkar H, Shujalpurkar A, Motiwale G. Calcifying Odontogenic Cyst: An Enigma. Int J Orofac Res [Internet]. 2023 Nov. 5 [cited 2023 Nov. 6];7(2):37-41. Available from: https://www.editorialmanager.in/index.php/ijofr/article/view/895

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